FIGN

Across TCGA patient cohorts, FIGN protein abundance is significantly associated with the RNA expression of many other genes, with 1,062 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FIGN-associated genes across cancer lineages are PAPLN, PRORP, and REC8. Each is linked with FIGN in more than 1 cancer types. Because this analysis shows association rather than direction, both FIGN-to-partner and partner-to-FIGN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FIGN versus PAPLN in LUAD, with a Pearson correlation of -0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FIGN→partner) and Y-score (partner→FIGN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PAPLN →	-1.131	-0.980	.007	<.001	3	1
LUAD	PRORP →	-0.488	-1.031	.005	<.001	3	1
LUAD	REC8 →	-0.979	-1.232	.006	.001	3	1
LUAD	OXT →	-1.348	-0.926	.001	.002	3	1
LUAD	KIR3DX1 →	-0.091	-1.022	.008	.002	3	1
LUAD	NUMBL →	-0.901	-1.003	.004	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,062 associations by consensus.

FIGN vs PAPLN — LUAD

Explore this scatter interactively →