FIGLA

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, FIGLA Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated FIGLA data layer compared with 20 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher FIGLA Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FIGLA expression acts as an unfavorable survival marker.

UCEC are the cancer types where FIGLA Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECOSMedianIV0.2310.592.0366view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration