FIGLA

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FIGLA RNA expression is significantly associated with the go_rna of many other GO terms, with 684 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FIGLA-associated GO terms across cancer lineages are Histamine metabolic process, Blood vessel endothelial cell fate specification, and Regulation of cardiac muscle cell proliferation. Each is linked with FIGLA in more than 2 cancer types. Because this analysis shows association rather than direction, both FIGLA-to-partner and partner-to-FIGLA results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FIGLA→partner) and Y-score (partner→FIGLA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaHistamine metabolic process →+1.457+0.405<.001.00933
BONEBlood vessel endothelial cell fate specification →-0.246-0.127<.001.00333
LUNG_SCLCRegulation of cardiac muscle cell proliferation →-0.099-0.081<.001<.00133
BONELeukocyte chemotaxis →-0.119-0.150.002.00933
BONERegulation of fibroblast growth factor receptor signaling pathway →-0.232-0.097<.001.00133
BONEPositive regulation of alpha-beta T cell activation →-0.080-0.125.001.00433
Each partner links to its Q-omics profile. Showing the 6 strongest of 684 associations by consensus.

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