FIG4

Across TCGA patient cohorts, FIG4 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,571 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible FIG4-associated proteins across cancer lineages are ARID1B, STX7, and PREP. Each is linked with FIG4 in more than 4 cancer types. Because this analysis shows association rather than direction, both FIG4-to-partner and partner-to-FIG4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FIG4 versus ARID1B in HNSC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FIG4→partner) and Y-score (partner→FIG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ARID1B →	+0.228	+0.470	<.001	<.001	3	5
GBM	STX7 →	+0.477	+0.586	<.001	<.001	3	5
OV	PREP →	+0.419	+0.542	<.001	<.001	3	5
COAD	MRPL15 →	-0.492	-0.345	<.001	<.001	3	4
BRCA	MTERF3 →	-0.509	-0.506	.001	<.001	3	4
OV	DRG2 →	+0.344	+0.687	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,571 associations by consensus.

FIG4 vs ARID1B — HNSC

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