FIBP

Across TCGA pan-cancer cohorts, FIBP mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FIBP data layer compared with 25 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher FIBP mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated FIBP expression acts as an unfavorable survival marker, although some lineages such as LSCC and PDAC show a favorable association.

LSCC, HNSC, and PDAC are the cancer types where FIBP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	All	0.880	0.577	<.001	67	view →
HNSC	DFS	Median	All	0.535	0.730	.009	37	view →
PDAC	OS	Quartile	All	0.697	0.291	.003	32	view →
GBM	DFS	Tertile	All	0.480	0.235	.001	16	view →
CCRCC	OS	Quartile	II,III,IV	0.977	0.104	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FIBP–LSCC (DFS)

Open the LSCC breakdown →