FIBIN

Across TCGA patient cohorts, FIBIN protein abundance is significantly associated with the RNA expression of many other genes, with 7,720 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FIBIN-associated genes across cancer lineages are TNFAIP6, MEDAG, and CRISPLD2. Each is linked with FIBIN in more than 4 cancer types. Because this analysis shows association rather than direction, both FIBIN-to-partner and partner-to-FIBIN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FIBIN versus TNFAIP6 in LSCC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FIBIN→partner) and Y-score (partner→FIBIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TNFAIP6 →	+1.337	+0.738	<.001	<.001	3	5
LUAD	MEDAG →	+0.869	+0.296	<.001	.002	3	4
BRCA	CRISPLD2 →	+1.016	+0.682	<.001	<.001	3	4
LSCC	PDGFRL →	+1.105	+0.667	<.001	<.001	3	4
GBM	PCOLCE →	+1.200	+0.409	.001	.003	3	4
BRCA	RARRES2 →	+1.104	+0.622	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,720 associations by consensus.

FIBIN vs TNFAIP6 — LSCC

Explore this scatter interactively →