FIBCD1

Across TCGA patient cohorts, FIBCD1 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. COAD shows the largest number of these associations.

The most reproducible FIBCD1-associated genes across cancer lineages are ASNS, Notch1, and p62 Lck ligand. Each is linked with FIBCD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FIBCD1-to-partner and partner-to-FIBCD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by FIBCD1-low versus FIBCD1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FIBCD1→partner) and Y-score (partner→FIBCD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ASNS →	+0.600	+3.178	.002	.010	3	2
UCEC	Notch1 →	+0.224	+3.013	.002	.018	3	1
UCEC	p62 Lck ligand →	+0.420	+3.169	.013	.018	3	1
COAD	MAPK_pT202_Y204 →	-0.481	-3.161	.047	.019	3	1
COAD	PKC-b-II_pS660 →	-0.500	-3.161	.004	.019	3	1
UCEC	c-Kit →	-0.244	-3.321	.046	.010	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

ASNS by FIBCD1 expression — COAD

Explore this box plot interactively →