FHOD3

Across TCGA cell cohorts, FHOD3 mutation is significantly associated with the RNA expression of many other genes, with 747 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FHOD3-associated genes across cancer lineages are LRIT2, CHST1, and ZNF20. Each is linked with FHOD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FHOD3-to-partner and partner-to-FHOD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LRIT2 grouped by FHOD3-low versus FHOD3-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FHOD3→partner) and Y-score (partner→FHOD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	LRIT2 →	+0.036	+5.087	<.001	.004	3	2
BLOOD_Leukemia	CHST1 →	+0.758	+3.684	<.001	.005	3	2
BLOOD_Lymphoma	ZNF20 →	+0.829	+2.533	.005	.005	3	2
LARGE_INTESTINE	NUP88 →	+0.561	+2.544	<.001	<.001	3	2
LARGE_INTESTINE	FRG1 →	+0.391	+2.458	.001	<.001	3	2
LARGE_INTESTINE	UFSP2 →	+0.526	+1.949	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 747 associations by consensus.

LRIT2 by FHOD3 expression — URINARY_TRACT

Explore this box plot interactively →