FHOD1

Across TCGA pan-cancer cohorts, FHOD1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated FHOD1 data layer compared with 23 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher FHOD1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated FHOD1 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

HNSC, LSCC, and COAD are the cancer types where FHOD1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Quartile	All	0.785	0.520	.011	14	view →
LSCC	DFS	Quartile	II,III,IV	0.753	1.000	.007	13	view →
COAD	DFS	Tertile	II,III,IV	0.941	1.000	.041	6	view →
GBM	OS	Quartile	All	0.351	0.632	.032	3	view →
CCRCC	OS	Quartile	II,III,IV	0.680	0.993	.016	2	view →
LUAD	OS	Quartile	II,III,IV	0.299	0.687	.033	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

FHOD1–HNSC (OS)

Open the HNSC breakdown →