FHOD1

Across TCGA patient cohorts, FHOD1 mutation is significantly associated with the total protein of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FHOD1-associated genes across cancer lineages are ACC1, PCNA, and YAP_pS127. Each is linked with FHOD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FHOD1-to-partner and partner-to-FHOD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACC1 grouped by FHOD1-low versus FHOD1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FHOD1→partner) and Y-score (partner→FHOD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ACC1 →	+0.321	+3.000	.013	.034	3	2
SKCM	PCNA →	+0.264	+2.321	.001	.032	3	2
SKCM	YAP_pS127 →	-0.348	-2.321	.021	.033	3	2
SKCM	Cyclin-B1 →	+0.586	+3.459	<.001	.004	3	2
UCEC	eIF4E →	+0.172	+3.598	.011	.001	3	2
UCEC	Ku80 →	+0.223	+1.729	.003	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

ACC1 by FHOD1 expression — SKCM

Explore this box plot interactively →