FHL5

Across TCGA patient cohorts, FHL5 protein abundance is significantly associated with the RNA expression of many other genes, with 14,669 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FHL5-associated genes across cancer lineages are CLEC14A, ADH1B, and ABCA8. Each is linked with FHL5 in more than 8 cancer types. Because this analysis shows association rather than direction, both FHL5-to-partner and partner-to-FHL5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FHL5 versus CLEC14A in CCRCC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FHL5→partner) and Y-score (partner→FHL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	CLEC14A →	+0.879	+0.565	<.001	<.001	3	9
OV	ADH1B →	+3.004	+0.744	<.001	.006	3	9
UCEC	ABCA8 →	+1.603	+1.024	<.001	<.001	3	8
UCEC	CCL14 →	+0.597	+1.201	<.001	<.001	3	8
UCEC	C7 →	+2.045	+0.984	<.001	<.001	3	8
HNSC	CASQ2 →	+1.280	+0.426	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,669 associations by consensus.

FHL5 vs CLEC14A — CCRCC

Explore this scatter interactively →