Across TCGA patient cohorts, FHL3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,322 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FHL3-associated proteins across cancer lineages are ANGPTL2, LAMB1, and LMCD1. Each is linked with FHL3 in more than 8 cancer types. Because this analysis shows association rather than direction, both FHL3-to-partner and partner-to-FHL3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FHL3→partner) and Y-score (partner→FHL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ANGPTL2 →	+0.658	+0.477	<.001	<.001	3	8
CCRCC	LAMB1 →	+0.481	+0.849	<.001	<.001	3	8
COAD	LMCD1 →	+0.683	+1.184	<.001	<.001	3	8
OV	FN1 →	+1.097	+0.933	<.001	<.001	3	8
BRCA	SERPINH1 →	+0.563	+0.727	<.001	<.001	3	8
CCRCC	PDLIM7 →	+0.778	+0.738	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,322 associations by consensus.

Exploration

FHL3 survival (RNA) · tumor vs normal (RNA) · all FHL3 data types