Across TCGA patient cohorts, FHL3 mutation is significantly associated with the RNA expression of many other genes, with 596 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FHL3-associated genes across cancer lineages are MIR548A3, RNA5SP411, and IMP3P2. Each is linked with FHL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FHL3-to-partner and partner-to-FHL3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FHL3→partner) and Y-score (partner→FHL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR548A3 →	+0.350	+3.411	<.001	.009	3	2
UCEC	RNA5SP411 →	+1.170	+2.393	<.001	.002	3	2
UCEC	IMP3P2 →	+0.266	+2.440	<.001	.001	3	2
CESC	KRTAP10-2 →	+0.377	+3.874	<.001	.004	3	1
CESC	RNU6-644P →	+0.354	+3.608	<.001	.004	3	1
CESC	OR5S1P →	+0.049	+3.779	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 596 associations by consensus.

Exploration

FHL3 survival (RNA) · tumor vs normal (RNA) · all FHL3 data types