Across TCGA cell cohorts, FHL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,328 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FHL3-associated GO terms across cancer lineages are Positive regulation of supramolecular fiber organization, Collagen fibril organization, and Positive regulation of cytoskeleton organization. Each is linked with FHL3 in more than 13 cancer types. Because this analysis shows association rather than direction, both FHL3-to-partner and partner-to-FHL3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FHL3→partner) and Y-score (partner→FHL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of supramolecular fiber organization →	+0.089	+0.956	<.001	.003	3	14
LUNG_NSCLC_LUSC	Collagen fibril organization →	+0.315	+1.689	.004	<.001	3	14
LUNG_NSCLC_LUSC	Positive regulation of cytoskeleton organization →	+0.073	+1.245	.008	.001	3	13
LUNG_NSCLC_LUSC	Positive regulation of stress fiber assembly →	+0.140	+1.439	.001	<.001	3	13
LUNG_NSCLC_LUSC	Integrin-mediated signaling pathway →	+0.167	+1.368	.001	<.001	3	13
LUNG_NSCLC_LUSC	Positive regulation of actin filament bundle assembly →	+0.132	+1.211	.003	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,328 associations by consensus.

Exploration

FHL3 survival (RNA) · tumor vs normal (RNA) · all FHL3 data types