FHL2

Across TCGA patient cohorts, FHL2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,980 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FHL2-associated proteins across cancer lineages are LIMA1_S686, TNKS1BP1_S1138, and MYO1E. Each is linked with FHL2 in more than 5 cancer types. Because this analysis shows association rather than direction, both FHL2-to-partner and partner-to-FHL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FHL2 versus LIMA1_S686 in OV, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FHL2→partner) and Y-score (partner→FHL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LIMA1_S686 →	+1.085	+0.862	.006	.007	3	6
LUAD	TNKS1BP1_S1138 →	+0.722	+0.922	<.001	<.001	3	5
GBM	MYO1E →	+0.454	+0.976	<.001	<.001	3	5
BRCA	NOL10 →	-0.330	-0.971	.002	.002	3	5
LSCC	P3H4 →	+0.586	+0.823	<.001	<.001	3	5
GBM	PLOD1 →	+0.623	+0.763	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,980 associations by consensus.

FHL2 vs LIMA1_S686 — OV

Explore this scatter interactively →