FHL1

Across TCGA patient cohorts, FHL1 RNA expression is significantly associated with the RNA expression of many other genes, with 19,356 significant associations in total. THYM shows the largest number of these associations.

The most reproducible FHL1-associated genes across cancer lineages are MAP7D3, SYNE1, and ZEB1. Each is linked with FHL1 in more than 30 cancer types. Because this analysis shows association rather than direction, both FHL1-to-partner and partner-to-FHL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FHL1 versus MAP7D3 in KICH, with a Pearson correlation of 0.69.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FHL1→partner) and Y-score (partner→FHL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KICH	MAP7D3 →	+1.454	+1.770	<.001	<.001	3	31
THCA	SYNE1 →	+1.377	+2.269	<.001	<.001	3	31
STAD	ZEB1 →	+1.479	+2.337	<.001	<.001	3	31
THYM	ATXN1 →	+1.048	+1.937	<.001	<.001	3	31
THYM	MPDZ →	+1.367	+1.660	<.001	<.001	3	30
UCS	SACS →	+1.217	+1.408	<.001	<.001	3	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,356 associations by consensus.

FHL1 vs MAP7D3 — KICH

Explore this scatter interactively →