FHL1

Across TCGA patient cohorts, FHL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 23,743 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FHL1-associated proteins across cancer lineages are CNN1, HSPB6, and TPM1. Each is linked with FHL1 in more than 8 cancer types. Because this analysis shows association rather than direction, both FHL1-to-partner and partner-to-FHL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FHL1 versus CNN1 in COAD, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FHL1→partner) and Y-score (partner→FHL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CNN1 →	+1.178	+1.079	<.001	<.001	3	9
COAD	HSPB6 →	+1.017	+0.868	<.001	<.001	3	9
COAD	TPM1 →	+0.971	+1.116	<.001	<.001	3	9
UCEC	PRKG1 →	+0.780	+1.568	<.001	<.001	3	8
HNSC	PYGM →	+0.948	+1.488	<.001	<.001	3	8
UCEC	PPP1R12B →	+1.037	+1.568	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,743 associations by consensus.

FHL1 vs CNN1 — COAD

Explore this scatter interactively →