FHL1

Across TCGA patient cohorts, FHL1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,676 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FHL1-associated genes across cancer lineages are SORBS1, CNRIP1, and JAM2. Each is linked with FHL1 in more than 9 cancer types. Because this analysis shows association rather than direction, both FHL1-to-partner and partner-to-FHL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FHL1 versus SORBS1 in COAD, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FHL1→partner) and Y-score (partner→FHL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SORBS1 →	+1.730	+1.052	<.001	<.001	3	10
UCEC	CNRIP1 →	+0.959	+1.349	<.001	<.001	3	9
BRCA	JAM2 →	+0.947	+0.886	<.001	<.001	3	9
HNSC	PI16 →	+1.458	+1.280	<.001	<.001	3	9
OV	MFAP4 →	+1.651	+0.732	<.001	<.001	3	9
OV	CHRDL1 →	+2.170	+0.936	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,676 associations by consensus.

FHL1 vs SORBS1 — COAD

Explore this scatter interactively →