FHDC1

Across TCGA cell cohorts, FHDC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,447 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible FHDC1-associated GO terms across cancer lineages are Regulation of myoblast fusion, Regulation of syncytium formation by plasma membrane fusion, and Establishment of epithelial cell apical/basal polarity. Each is linked with FHDC1 in more than 10 cancer types. Because this analysis shows association rather than direction, both FHDC1-to-partner and partner-to-FHDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by FHDC1-low versus FHDC1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FHDC1→partner) and Y-score (partner→FHDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of myoblast fusion →	+0.100	+1.368	.001	.007	3	11
BLOOD_Lymphoma	Regulation of syncytium formation by plasma membrane fusion →	+0.091	+0.350	<.001	.001	3	11
URINARY_TRACT	Establishment of epithelial cell apical/basal polarity →	-0.202	-1.095	<.001	<.001	3	10
SKIN	Negative regulation of endoplasmic reticulum unfolded protein response →	+0.059	+1.312	<.001	.002	3	10
LUNG_SCLC	Negative regulation of inflammatory response to wounding →	+0.211	+1.829	<.001	<.001	3	9
PANCREAS	Response to indole-3-methanol →	+0.177	+1.201	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,447 associations by consensus.

Regulation of myoblast fusion by FHDC1 expression — LUNG_SCLC

Explore this box plot interactively →