FHAD1

Across TCGA pan-cancer cohorts, FHAD1 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated FHAD1 data layer compared with 23 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher FHAD1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FHAD1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

TGCT, UCEC, and SARC are the cancer types where FHAD1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
TGCT	OS	Median	All	0.083	0.969	<.001	12	view →
UCEC	DFS	Median	All	0.980	0.890	.020	10	view →
SARC	DFS	Median	All	0.095	0.632	.002	6	view →
LIHC	OS	Median	All	0.554	0.781	.010	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

FHAD1–TGCT (OS)

Open the TGCT breakdown →