FGR

Across TCGA pan-cancer cohorts, FGR mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated FGR data layer compared with 30 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher FGR mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated FGR expression acts as an unfavorable survival marker, although some lineages such as CCRCC and UCEC show a favorable association.

LUAD, COAD, and CCRCC are the cancer types where FGR mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	III,IV	0.327	0.811	<.001	33	view →
COAD	DFS	Median	All	0.874	1.000	.035	24	view →
CCRCC	DFS	Median	All	1.000	0.809	.005	17	view →
UCEC	OS	Median	II,III,IV	1.000	0.691	.035	8	view →
PDAC	OS	Median	III,IV	0.360	0.829	.008	7	view →
GBM	OS	Quartile	All	0.889	1.000	.012	3	view →
HNSC	DFS	Median	III,IV	0.937	1.000	.035	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

FGR–LUAD (OS)

Open the LUAD breakdown →