FGR

Across TCGA cell cohorts, FGR RNA expression is significantly associated with the go_rna of many other GO terms, with 2,593 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FGR-associated GO terms across cancer lineages are Maintenance of protein localization in organelle, Detection of bacterial lipoprotein, and Complement-mediated synapse pruning. Each is linked with FGR in more than 7 cancer types. Because this analysis shows association rather than direction, both FGR-to-partner and partner-to-FGR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maintenance of protein localization in organelle grouped by FGR-low versus FGR-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FGR→partner) and Y-score (partner→FGR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Maintenance of protein localization in organelle →	+0.123	+0.189	<.001	.001	3	8
BREAST	Detection of bacterial lipoprotein →	+0.860	+0.127	<.001	<.001	3	6
SOFT_TISSUE	Complement-mediated synapse pruning →	+1.562	+0.283	<.001	.007	3	6
BLOOD_Leukemia	tRNA 5'-leader removal →	-0.052	-1.617	.006	.003	3	6
SOFT_TISSUE	Maintenance of protein location in cell →	+0.134	+0.180	<.001	.006	2	7
SOFT_TISSUE	Maintenance of protein location →	+0.140	+0.179	<.001	.006	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,593 associations by consensus.

Maintenance of protein localization in organelle by FGR expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →