FGL2

Across TCGA cell cohorts, FGL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,961 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FGL2-associated GO terms across cancer lineages are Peptidyl-lysine modification, Pallium development, and Regulation of glucan biosynthetic process. Each is linked with FGL2 in more than 5 cancer types. Because this analysis shows association rather than direction, both FGL2-to-partner and partner-to-FGL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-lysine modification grouped by FGL2-low versus FGL2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FGL2→partner) and Y-score (partner→FGL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Peptidyl-lysine modification →	+0.042	+0.112	.002	.003	3	5
LUNG_SCLC	Pallium development →	+0.074	+0.102	<.001	<.001	3	5
URINARY_TRACT	Regulation of glucan biosynthetic process →	+0.056	+0.073	.001	.002	3	5
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.137	-0.120	<.001	<.001	3	5
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.134	+0.110	.002	.003	3	5
URINARY_TRACT	Regulation of glycogen biosynthetic process →	+0.056	+0.073	.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,961 associations by consensus.

Peptidyl-lysine modification by FGL2 expression — LUNG_SCLC

Explore this box plot interactively →