FGL1

Across TCGA patient cohorts, FGL1 mutation is significantly associated with the RNA expression of many other genes, with 1,931 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FGL1-associated genes across cancer lineages are MIR147A, RN7SL567P, and MIR2276. Each is linked with FGL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FGL1-to-partner and partner-to-FGL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR147A grouped by FGL1-low versus FGL1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGL1→partner) and Y-score (partner→FGL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR147A →	+0.486	+4.308	<.001	.009	3	2
BLCA	RN7SL567P →	+0.162	+5.018	<.001	.004	3	2
BLCA	MIR2276 →	+0.323	+4.588	.001	.008	3	2
UCEC	RNA5SP161 →	+0.831	+2.113	<.001	.002	3	2
UCEC	RNA5SP492 →	+0.262	+2.261	<.001	.007	3	2
UCEC	IL21-AS1 →	+0.106	+2.480	.009	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,931 associations by consensus.

MIR147A by FGL1 expression — COAD

Explore this box plot interactively →