FGL1

Across TCGA cell cohorts, FGL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 935 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible FGL1-associated GO terms across cancer lineages are Vesicle docking involved in exocytosis, Cellular response to toxic substance, and Cellular detoxification. Each is linked with FGL1 in more than 5 cancer types. Because this analysis shows association rather than direction, both FGL1-to-partner and partner-to-FGL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle docking involved in exocytosis grouped by FGL1-low versus FGL1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FGL1→partner) and Y-score (partner→FGL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Vesicle docking involved in exocytosis →	+0.078	+4.468	.002	.002	3	6
LIVER	Cellular response to toxic substance →	+0.108	+4.591	.002	<.001	3	5
LIVER	Cellular detoxification →	+0.128	+4.591	.001	<.001	3	5
LIVER	Cellular oxidant detoxification →	+0.136	+4.612	.002	<.001	3	4
LIVER	Lipid oxidation →	+0.065	+4.231	.009	.001	2	5
LIVER	Regulation of plasminogen activation →	-0.266	-4.603	.005	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 935 associations by consensus.

Vesicle docking involved in exocytosis by FGL1 expression — LIVER

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