FGGY

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FGGY protein abundance is significantly associated with the RNA expression of many other genes, with 18,642 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FGGY-associated genes across cancer lineages are FAM83D, CDCA3, and TTK. Each is linked with FGGY in more than 6 cancer types. Because this analysis shows association rather than direction, both FGGY-to-partner and partner-to-FGGY results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FGGY versus FAM83D in BRCA, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGGY→partner) and Y-score (partner→FGGY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAFAM83D →-1.358-0.367<.001<.00137
BRCACDCA3 →-1.267-0.405<.001<.00137
GBMTTK →-1.135-0.360<.001<.00137
BRCACENPF →-1.336-0.390<.001<.00137
BRCAKIF14 →-1.353-0.460<.001<.00137
GBMKNSTRN →-0.712-0.372<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,642 associations by consensus.

FGGY vs FAM83D — BRCA

Per-sample scatter of FGGY vs FAM83D in BRCA (Pearson r = -0.32).

Explore this scatter interactively →

Exploration