FGG

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FGG RNA expression is significantly associated with the protein abundance of many other proteins, with 12,561 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FGG-associated proteins across cancer lineages are F13B, SUN1, and NELFA. Each is linked with FGG in more than 3 cancer types. Because this analysis shows association rather than direction, both FGG-to-partner and partner-to-FGG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FGG versus F13B in GBM, with a Pearson correlation of 0.19.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FGG→partner) and Y-score (partner→FGG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMF13B →+0.452+0.105.001.00534
LSCCSUN1 →-0.259-1.749.003.00433
LSCCNELFA →-0.193-1.892<.001<.00133
LSCCSERPIND1 →+0.550+2.305<.001<.00133
GBMHABP2 →+0.435+0.116<.001.00733
LSCCIRF2BPL →-0.275-1.470<.001.00333
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,561 associations by consensus.

FGG vs F13B — GBM

Per-sample scatter of FGG vs F13B in GBM (Pearson r = 0.19).

Explore this scatter interactively →

Exploration