FGG

Across TCGA patient cohorts, FGG protein abundance is significantly associated with the RNA expression of many other genes, with 12,764 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FGG-associated genes across cancer lineages are IL6, ADAMTS4, and FPR2. Each is linked with FGG in more than 6 cancer types. Because this analysis shows association rather than direction, both FGG-to-partner and partner-to-FGG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FGG versus IL6 in CCRCC, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGG→partner) and Y-score (partner→FGG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	IL6 →	+1.581	+0.657	<.001	.003	3	7
OV	ADAMTS4 →	+1.053	+1.387	<.001	<.001	3	6
GBM	FPR2 →	+1.038	+0.759	<.001	<.001	3	6
OV	FOSL1 →	+1.093	+1.071	.001	<.001	3	6
CCRCC	SOCS3 →	+1.104	+0.963	<.001	<.001	3	6
OV	SLC2A3 →	+1.213	+1.215	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,764 associations by consensus.

FGG vs IL6 — CCRCC

Explore this scatter interactively →