FGFR3P5

Across TCGA pan-cancer cohorts, FGFR3P5 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated FGFR3P5 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher FGFR3P5 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FGFR3P5 expression acts as an unfavorable survival marker, although some lineages such as PAAD show a favorable association.

COAD, UVM, and LIHC are the cancer types where FGFR3P5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	IV	0.039	0.660	<.001	108	view →
UVM	OS	Tertile	All	0.348	0.719	.011	72	view →
LIHC	OS	Tertile	II,III,IV	0.150	0.723	<.001	72	view →
PAAD	DFS	Tertile	II,III,IV	0.839	0.254	.006	36	view →
PCPG	OS	Tertile	All	0.505	0.946	<.001	27	view →
ACC	OS	Tertile	All	0.422	0.855	<.001	24	view →
SARC	OS	Tertile	All	0.249	0.738	<.001	21	view →
SKCM	OS	Tertile	III,IV	0.178	0.420	.020	18	view →
THCA	DFS	Tertile	All	0.552	0.845	<.001	18	view →
LUSC	OS	Tertile	III,IV	0.464	0.705	.019	18	view →
LGG	OS	Tertile	All	0.333	0.830	.012	9	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

FGFR3P5–COAD (OS)

Open the COAD breakdown →