FGFR2

Across TCGA patient cohorts, FGFR2 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,628 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FGFR2-associated proteins across cancer lineages are PKP4, TRIM2, and C1orf226_S198. Each is linked with FGFR2 in more than 4 cancer types. Because this analysis shows association rather than direction, both FGFR2-to-partner and partner-to-FGFR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FGFR2 versus PKP4 in BRCA, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FGFR2→partner) and Y-score (partner→FGFR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PKP4 →	+0.434	+1.175	<.001	<.001	3	5
HNSC	TRIM2 →	+0.685	+1.170	<.001	<.001	3	5
BRCA	C1orf226_S198 →	+1.251	+1.208	<.001	<.001	3	5
HNSC	EPB41L1 →	+0.654	+0.800	<.001	<.001	3	5
BRCA	MAP7D1_S460 →	-0.583	-1.279	<.001	<.001	3	5
BRCA	VEZF1 →	+0.317	+1.150	.004	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,628 associations by consensus.

FGFR2 vs PKP4 — BRCA

Explore this scatter interactively →