FGFR2

Across TCGA cell cohorts, FGFR2 RNA expression is significantly associated with the RNA expression of many other genes, with 8,080 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FGFR2-associated genes across cancer lineages are FGFR3, STON2, and HPCAL1. Each is linked with FGFR2 in more than 8 cancer types. Because this analysis shows association rather than direction, both FGFR2-to-partner and partner-to-FGFR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FGFR2 versus FGFR3 in URINARY_TRACT, with a Pearson correlation of 0.55.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGFR2→partner) and Y-score (partner→FGFR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	FGFR3 →	+4.217	+2.902	<.001	<.001	3	9
OVARY	STON2 →	+2.078	+2.995	<.001	<.001	3	8
LUNG_NSCLC_LUSC	HPCAL1 →	-2.345	-3.237	<.001	<.001	3	7
URINARY_TRACT	MAP7 →	+2.988	+3.137	<.001	<.001	3	7
URINARY_TRACT	BTG2 →	+2.491	+2.045	<.001	<.001	3	7
SOFT_TISSUE	EPB41L5 →	+1.271	+3.486	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,080 associations by consensus.

FGFR2 vs FGFR3 — URINARY_TRACT

Explore this scatter interactively →