FGFR1OP2

Across TCGA pan-cancer cohorts, FGFR1OP2 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated FGFR1OP2 data layer compared with 20 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher FGFR1OP2 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated FGFR1OP2 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and GBM show a favorable association.

CCRCC, GBM, and HNSC are the cancer types where FGFR1OP2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	All	0.941	0.724	<.001	56	view →
GBM	OS	Median	All	0.862	0.770	.016	8	view →
HNSC	DFS	Quartile	II,III,IV	0.693	0.881	.022	7	view →
LUAD	DFS	Median	All	0.774	0.512	.003	7	view →
PDAC	DFS	Tertile	IV	0.558	0.225	.024	5	view →
LSCC	DFS	Quartile	All	1.000	0.546	.026	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

FGFR1OP2–CCRCC (OS)

Open the CCRCC breakdown →