FGFR1

Across TCGA cell cohorts, FGFR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,219 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FGFR1-associated GO terms across cancer lineages are Regulation of phospholipase activity, Positive regulation of phospholipase activity, and Positive regulation of lipase activity. Each is linked with FGFR1 in more than 16 cancer types. Because this analysis shows association rather than direction, both FGFR1-to-partner and partner-to-FGFR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of phospholipase activity grouped by FGFR1-low versus FGFR1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FGFR1→partner) and Y-score (partner→FGFR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of phospholipase activity →	+1.608	+3.395	<.001	<.001	3	17
BLOOD_Lymphoma	Positive regulation of phospholipase activity →	+1.608	+3.395	<.001	<.001	3	17
LIVER	Positive regulation of lipase activity →	+0.374	+2.521	<.001	<.001	3	12
CNS	Calcium-independent cell-matrix adhesion →	+0.193	+1.391	<.001	.001	3	11
LUNG_NSCLC_LUSC	Protein-DNA complex assembly →	+0.059	+4.198	<.001	<.001	3	11
BREAST	Regulation of chromosome organization →	+0.068	+1.880	<.001	.007	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,219 associations by consensus.

Regulation of phospholipase activity by FGFR1 expression — BLOOD_Lymphoma

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