FGF9

Across TCGA pan-cancer cohorts, FGF9 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated FGF9 data layer compared with 2 for mutation status.

The strongest signal is observed in mesothelioma (MESO), where higher FGF9 RNA is associated with better overall survival. In most high-consensus cancer types, elevated FGF9 expression acts as an unfavorable survival marker, although some lineages such as MESO and PAAD show a favorable association.

MESO, UVM, and ACC are the cancer types where FGF9 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	All	0.476	0.235	.001	51	view →
UVM	DFS	Quartile	III,IV	0.442	0.930	.006	46	view →
ACC	DFS	Median	All	0.396	0.768	<.001	38	view →
LUSC	OS	Quartile	III,IV	0.223	0.558	.003	25	view →
LIHC	OS	Median	All	0.418	0.667	<.001	23	view →
PAAD	DFS	Quartile	All	0.615	0.401	.008	22	view →
BRCA	OS	Median	All	0.629	0.540	.009	20	view →
LGG	OS	Quartile	All	0.606	0.463	.003	13	view →
HNSC	DFS	Median	All	0.576	0.725	.015	13	view →
CHOL	DFS	Tertile	All	0.416	0.154	.026	12	view →
SKCM	DFS	Median	IV	0.763	0.187	.006	8	view →
THCA	DFS	Tertile	IV	0.421	0.865	.006	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

FGF9–MESO (OS)

Open the MESO breakdown →