Across TCGA patient cohorts, FGF3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,355 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible FGF3-associated GO terms across cancer lineages are Regulation of cell fate commitment, Epithelial to mesenchymal transition, and Negative regulation of Wnt signaling pathway. Each is linked with FGF3 in more than 11 cancer types. Because this analysis shows association rather than direction, both FGF3-to-partner and partner-to-FGF3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF3→partner) and Y-score (partner→FGF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Regulation of cell fate commitment →	+0.065	+0.432	<.001	<.001	3	12
STAD	Epithelial to mesenchymal transition →	+0.071	+0.521	<.001	.001	3	12
STAD	Negative regulation of Wnt signaling pathway →	+0.063	+0.529	<.001	<.001	3	12
STAD	Axis elongation →	+0.067	+0.891	<.001	<.001	3	12
TGCT	Mesenchymal cell migration →	+0.057	+0.463	<.001	<.001	3	11
TGCT	Negative regulation of morphogenesis of an epithelium →	+0.080	+0.285	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,355 associations by consensus.

Exploration

FGF3 survival (RNA) · tumor vs normal (RNA) · all FGF3 data types