Across TCGA cell cohorts, FGF3 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FGF3-associated genes across cancer lineages are CST8, PZP, and METTL21C. Each is linked with FGF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FGF3-to-partner and partner-to-FGF3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF3→partner) and Y-score (partner→FGF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CST8 →	+0.021	+4.415	<.001	.007	3	1
LARGE_INTESTINE	PZP →	+0.030	+4.467	<.001	.004	3	1
LARGE_INTESTINE	METTL21C →	+0.155	+4.273	<.001	.006	3	1
LARGE_INTESTINE	FAM71B →	+0.005	+5.022	<.001	.002	3	1
LARGE_INTESTINE	OR2K2 →	+0.037	+4.095	<.001	.009	3	1
LARGE_INTESTINE	OR56B1 →	+0.020	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

FGF3 survival (RNA) · tumor vs normal (RNA) · all FGF3 data types