FGF2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FGF2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,392 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FGF2-associated genes across cancer lineages are ASPA, SGCA, and RBMS3. Each is linked with FGF2 in more than 7 cancer types. Because this analysis shows association rather than direction, both FGF2-to-partner and partner-to-FGF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FGF2 versus ASPA in UCEC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF2→partner) and Y-score (partner→FGF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECASPA →+0.907+1.317<.001<.00138
LUADSGCA →+0.895+0.578<.001<.00138
UCECRBMS3 →+0.964+1.240<.001<.00138
UCECNR2F2-AS1 →+0.732+0.743<.001<.00138
OVCBX7 →+0.642+0.700.007.00537
PDACFHL5 →+1.020+0.511<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,392 associations by consensus.

FGF2 vs ASPA — UCEC

Per-sample scatter of FGF2 vs ASPA in UCEC (Pearson r = 0.50).

Explore this scatter interactively →

Exploration