FGF19

Across TCGA patient cohorts, FGF19 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,629 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible FGF19-associated GO terms across cancer lineages are Mesenchyme morphogenesis, Embryonic appendage morphogenesis, and Negative regulation of canonical Wnt signaling pathway. Each is linked with FGF19 in more than 14 cancer types. Because this analysis shows association rather than direction, both FGF19-to-partner and partner-to-FGF19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mesenchyme morphogenesis grouped by FGF19-low versus FGF19-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF19→partner) and Y-score (partner→FGF19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mesenchyme morphogenesis →	+0.048	+0.707	<.001	<.001	3	14
ESCA	Embryonic appendage morphogenesis →	+0.047	+1.355	<.001	.001	2	15
STAD	Negative regulation of canonical Wnt signaling pathway →	+0.046	+0.682	<.001	<.001	3	12
STAD	Ventricular septum morphogenesis →	+0.053	+0.799	<.001	<.001	3	12
UCS	Cellular response to cholesterol →	+0.063	+2.039	<.001	.003	2	13
STAD	Mesonephros development →	+0.031	+0.633	<.001	.001	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,629 associations by consensus.

Mesenchyme morphogenesis by FGF19 expression — STAD

Explore this box plot interactively →