FGF19

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FGF19 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FGF19-associated genes across cancer lineages are CD4+ Tem. Each is linked with FGF19 in more than 1 cancer types. Because this analysis shows association rather than direction, both FGF19-to-partner and partner-to-FGF19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tem grouped by FGF19-low versus FGF19-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF19→partner) and Y-score (partner→FGF19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCD4+ Tem →+0.037+4.081<.001.01631
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CD4+ Tem by FGF19 expression — UCEC

Box plot of CD4+ Tem in FGF19-low vs FGF19-high samples in UCEC.

Explore this box plot interactively →

Exploration