FGF19

Across TCGA cell cohorts, FGF19 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible FGF19-associated genes across cancer lineages are GZMK. Each is linked with FGF19 in more than 1 cancer types. Because this analysis shows association rather than direction, both FGF19-to-partner and partner-to-FGF19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GZMK grouped by FGF19-low versus FGF19-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF19→partner) and Y-score (partner→FGF19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	GZMK →	+0.056	+5.169	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

GZMK by FGF19 expression — BREAST

Explore this box plot interactively →