FGF17

Across TCGA patient cohorts, FGF17 mutation is significantly associated with the RNA expression of many other genes, with 310 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FGF17-associated genes across cancer lineages are RNA5SP422, RNA5SP416, and RAC1P1. Each is linked with FGF17 in more than 1 cancer types. Because this analysis shows association rather than direction, both FGF17-to-partner and partner-to-FGF17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP422 grouped by FGF17-low versus FGF17-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF17→partner) and Y-score (partner→FGF17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP422 →	+0.713	+2.671	.003	.002	3	2
UCEC	RNA5SP416 →	+0.682	+2.738	<.001	.003	3	2
SKCM	RAC1P1 →	+0.078	+4.970	<.001	.005	3	2
UCEC	MIR6803 →	+0.230	+5.156	<.001	.001	3	1
UCEC	SNX3P1Y →	+0.149	+5.156	<.001	.001	3	1
COAD	LCE1C →	+0.159	+4.246	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 310 associations by consensus.

RNA5SP422 by FGF17 expression — UCEC

Explore this box plot interactively →