FGF17

Across TCGA cell cohorts, FGF17 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FGF17-associated genes across cancer lineages are CDH20, SSMEM1, and OR1L6. Each is linked with FGF17 in more than 1 cancer types. Because this analysis shows association rather than direction, both FGF17-to-partner and partner-to-FGF17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDH20 grouped by FGF17-low versus FGF17-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF17→partner) and Y-score (partner→FGF17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CDH20 →	+0.196	+4.392	<.001	.004	3	1
LARGE_INTESTINE	SSMEM1 →	+0.023	+3.707	.008	.009	3	1
LARGE_INTESTINE	OR1L6 →	+0.022	+4.437	<.001	.004	3	1
LARGE_INTESTINE	FAM187B →	+0.031	+4.347	<.001	.001	3	1
LARGE_INTESTINE	ACTL7A →	+0.037	+3.823	<.001	.006	3	1
LARGE_INTESTINE	DEFB134 →	+0.017	+3.684	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

CDH20 by FGF17 expression — LARGE_INTESTINE

Explore this box plot interactively →