FGF14

Across TCGA patient cohorts, FGF14 mutation is significantly associated with the RNA expression of many other genes, with 2,353 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FGF14-associated genes across cancer lineages are RN7SL255P, SLC25A3P3, and ANKRD26P2. Each is linked with FGF14 in more than 2 cancer types. Because this analysis shows association rather than direction, both FGF14-to-partner and partner-to-FGF14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL255P grouped by FGF14-low versus FGF14-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF14→partner) and Y-score (partner→FGF14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RN7SL255P →	+0.535	+3.359	<.001	.003	3	3
LUAD	SLC25A3P3 →	+0.114	+3.303	.008	.004	3	3
READ	ANKRD26P2 →	+0.171	+5.421	<.001	.005	3	2
UCEC	PHF5A →	+0.570	+3.247	<.001	<.001	3	2
UCEC	CST3 →	-0.643	-3.959	.001	<.001	3	2
UCEC	WFDC2 →	-1.280	-2.796	.005	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,353 associations by consensus.

RN7SL255P by FGF14 expression — LUAD

Explore this box plot interactively →