FGF14

Across TCGA cell cohorts, FGF14 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FGF14-associated genes across cancer lineages are CST8, OR52E5, and OR1L6. Each is linked with FGF14 in more than 1 cancer types. Because this analysis shows association rather than direction, both FGF14-to-partner and partner-to-FGF14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CST8 grouped by FGF14-low versus FGF14-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF14→partner) and Y-score (partner→FGF14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CST8 →	+0.052	+4.969	<.001	.003	3	1
BLOOD_Leukemia	OR52E5 →	+0.012	+4.539	<.001	.007	3	1
LARGE_INTESTINE	OR1L6 →	+0.018	+4.022	<.001	.006	3	1
LARGE_INTESTINE	OR2J2 →	+0.016	+3.632	<.001	.003	3	1
LARGE_INTESTINE	TECRL →	+0.014	+3.977	<.001	.001	3	1
LARGE_INTESTINE	IQCF6 →	+0.228	+3.882	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

CST8 by FGF14 expression — BLOOD_Leukemia

Explore this box plot interactively →