FGF14-IT1

Across TCGA pan-cancer cohorts, FGF14-IT1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated FGF14-IT1 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher FGF14-IT1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FGF14-IT1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and PAAD show a favorable association.

COAD, KICH, and HNSC are the cancer types where FGF14-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	All	0.773	0.884	.002	66	view →
KICH	DFS	Tertile	All	0.584	0.962	.001	44	view →
HNSC	OS	Median	III,IV	0.497	0.285	.002	39	view →
BRCA	DFS	Tertile	All	0.570	1.000	.033	36	view →
PAAD	DFS	Median	All	0.380	0.167	.002	35	view →
LGG	OS	Median	All	0.945	0.846	<.001	35	view →
LIHC	OS	Tertile	All	0.322	0.609	.002	29	view →
OV	DFS	Tertile	All	0.619	0.509	.006	28	view →
MESO	DFS	Tertile	II,III,IV	0.359	0.749	.020	21	view →
THYM	DFS	Tertile	All	1.000	0.840	.019	20	view →
ACC	OS	Tertile	IV	0.327	0.633	.045	18	view →
KIRC	DFS	Tertile	IV	0.349	0.677	.001	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

FGF14-IT1–COAD (OS)

Open the COAD breakdown →