FGF14-AS2

Across TCGA pan-cancer cohorts, FGF14-AS2 RNA is linked to patient survival in 28 of 34 cancer types, making it the most broadly survival-associated FGF14-AS2 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher FGF14-AS2 RNA is associated with better overall survival. In most high-consensus cancer types, elevated FGF14-AS2 expression acts as an unfavorable survival marker, although some lineages such as KIRP and MESO show a favorable association.

KIRP, MESO, and KIRC are the cancer types where FGF14-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Tertile	All	0.834	0.620	<.001	119	view →
MESO	OS	Tertile	All	0.690	0.318	<.001	105	view →
KIRC	DFS	Median	All	0.689	0.565	<.001	103	view →
UVM	DFS	Tertile	All	0.779	0.401	<.001	60	view →
BRCA	OS	Median	All	0.947	0.899	.001	53	view →
PAAD	DFS	Tertile	All	0.425	0.186	<.001	49	view →
ACC	OS	Quartile	II,III,IV	0.911	0.257	.003	29	view →
BLCA	OS	Tertile	III,IV	0.265	0.486	.006	18	view →
OV	OS	Tertile	IV	0.533	0.286	.007	14	view →
SARC	OS	Tertile	All	0.794	0.662	.028	13	view →
LUAD	DFS	Quartile	III,IV	0.801	0.426	.008	12	view →
TGCT	DFS	Quartile	All	0.930	0.684	.018	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 28 lineages.

FGF14-AS2–KIRP (OS)

Open the KIRP breakdown →