FGF12

Across TCGA cell cohorts, FGF12 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,851 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FGF12-associated GO terms across cancer lineages are Gamma-aminobutyric acid signaling pathway, Regulation of neuronal action potential, and Calcium ion transport. Each is linked with FGF12 in more than 10 cancer types. Because this analysis shows association rather than direction, both FGF12-to-partner and partner-to-FGF12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Gamma-aminobutyric acid signaling pathway grouped by FGF12-low versus FGF12-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF12→partner) and Y-score (partner→FGF12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Gamma-aminobutyric acid signaling pathway →	-0.370	-1.767	<.001	.001	3	11
LARGE_INTESTINE	Regulation of neuronal action potential →	-0.403	-0.782	.008	.006	3	11
OESOPHAGUS	Calcium ion transport →	-0.081	-2.270	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Calcium ion transmembrane transport →	-0.075	-1.340	<.001	<.001	3	9
SOFT_TISSUE	Establishment of protein localization to membrane →	+0.063	+0.935	<.001	<.001	3	9
OESOPHAGUS	Regulation of nervous system process →	-0.088	-1.888	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,851 associations by consensus.

Gamma-aminobutyric acid signaling pathway by FGF12 expression — STOMACH

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