FGF12-AS3

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, FGF12-AS3 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated FGF12-AS3 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher FGF12-AS3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FGF12-AS3 expression acts as an unfavorable survival marker, although some lineages such as LGG and KIRP show a favorable association.

UCEC, LGG, and KIRP are the cancer types where FGF12-AS3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECDFSTertileAll0.4680.684<.00148view →
LGGDFSTertileAll0.5510.324<.00142view →
KIRPDFSQuartileAll0.9850.881.00635view →
ACCOSTertileII,III,IV0.2040.906.00429view →
CHOLDFSTertileAll0.8470.175.00218view →
STADOSQuartileAll0.3880.631.02012view →
THCADFSQuartileAll0.9060.976.00311view →
KICHDFSQuartileIII,IV0.7700.040.01011view →
SKCMDFSQuartileAll0.7100.574.00410view →
PAADDFSMedianIII,IV0.8930.470.0247view →
READDFSTertileAll0.2500.629.0416view →
KIRCDFSQuartileAll0.9110.799.0235view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

Exploration