FGF12-AS2

Across TCGA pan-cancer cohorts, FGF12-AS2 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated FGF12-AS2 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher FGF12-AS2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FGF12-AS2 expression acts as an unfavorable survival marker, although some lineages such as KIRC and LGG show a favorable association.

CESC, UVM, and KIRC are the cancer types where FGF12-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Tertile	All	0.695	0.853	<.001	78	view →
UVM	OS	Tertile	III,IV	0.234	0.762	.004	51	view →
KIRC	OS	Tertile	All	0.910	0.828	.001	37	view →
LUAD	DFS	Tertile	All	0.732	0.854	<.001	32	view →
LGG	DFS	Quartile	All	0.815	0.663	.002	31	view →
UCEC	OS	Tertile	All	0.832	0.890	.021	22	view →
KIRP	DFS	Median	IV	0.037	0.527	.004	21	view →
ESCA	OS	Quartile	II,III,IV	0.556	0.853	.001	20	view →
UCS	DFS	Median	II,III,IV	0.441	0.178	.009	20	view →
PRAD	DFS	Tertile	All	0.990	0.913	<.001	18	view →
ACC	DFS	Quartile	All	0.336	0.719	.011	16	view →
BLCA	DFS	Median	All	0.261	0.418	.027	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

FGF12-AS2–CESC (DFS)

Open the CESC breakdown →