FGF12-AS1

Across TCGA pan-cancer cohorts, FGF12-AS1 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated FGF12-AS1 data layer.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher FGF12-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FGF12-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and GBM show a favorable association.

CHOL, PAAD, and KIRC are the cancer types where FGF12-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CHOL	DFS	Tertile	II,III,IV	0.016	0.406	<.001	72	view →
PAAD	DFS	Tertile	II,III,IV	0.195	0.449	.001	63	view →
KIRC	OS	Tertile	II,III,IV	0.633	0.819	.008	51	view →
ACC	DFS	Tertile	All	0.308	0.639	.001	41	view →
BLCA	DFS	Tertile	III,IV	0.256	0.487	.003	36	view →
THCA	DFS	Tertile	II,III,IV	0.462	0.887	<.001	27	view →
SARC	OS	Tertile	All	0.575	0.879	.001	21	view →
CESC	OS	Tertile	All	0.533	0.802	.020	18	view →
UCEC	DFS	Tertile	All	0.395	0.681	.019	18	view →
KICH	DFS	Tertile	III,IV	0.065	0.835	.020	18	view →
ESCA	DFS	Median	II,III,IV	0.388	0.549	.016	17	view →
BRCA	DFS	Tertile	IV	0.824	0.232	.025	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

FGF12-AS1–CHOL (DFS)

Open the CHOL breakdown →